Current Advances in Endocrinology Metabolism


Insulin resistance contributes to the pathophysiology of diabetes. It is a hallmark of obesity, metabolic syndrome and other cardiovascular diseases. Direct and indirect methods of varying complexity are currently employed for these purposes. Endocrine disorders involve the body’s over production or under production of certain hormones while the metabolic disorders affect the body’s ability to process certain nutrients and vitamins. Endocrine disorders include several diseases like hypothyroidism, congenital adrenal hyperplasia, diseases of the parathyroid gland, diabetes mellitus, diseases of the adrenal glands (including Cushing’s syndrome and Addison’s disease), and ovarian dysfunction among others. Examples of metabolic disorders include cystic fibrosis, phenylketonuria (PKU), hyperlipidemia, gout, and rickets.


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