Asia Pacific Diabetes and Endocrinology Congress February 27-28, 2019 Tokyo, Japan

Passorn Sueyanyongsiri has completed her MD at the age of 25 years from Chulalongkorn University and postdoctoral studies from Mahidol University School of Medicine. She is the medical teacher in Surin hospital, Affiliated Institutes of Suranaree University of Technology, Thailand.

A decreased life-span of erythrocytes is associated with lower concentration of hemoglobin A1C (HbA1c). This research aims to study effect of hemoglobin E homozygote on HbA1c level of diabetic patients in Surin Hospital. A cross-sectional study was conducted from 2009 to 20016. Patient’s profile, fasting plasma glucose and HbA1c level were collected and divided in hemoglobin E homozygous group and control group. Each sample arm was classified into eight strata according to blood glucose level to compare HbA1c level in each subgroup. During 2009-20016, 81 diabetic patients with hemoglobin E homozygote were found from overall 353 negative dichlorophenol-indolephenol (DCIP) diabetic patients. There is no difference of sex, average age, duration of disease and fasting plasma glucose between hemoglobin E homozygote and control group. Patients with hemoglobin E homozygous group had lower HbA1c level than those of control group (P<0.05). Conclusion: Since HbA1c levels is presently the best indicator of long term glycemic control. With similar fasting plasma glucose, hemoglobin E homozygote is associated with lower HbA1c level.

Tarek Amin Abdulhamid El-shazly has completed M.D in Internal Medicine, Mansoura University, Thesis titled: Platelet Disorders in Liver Cirrhosis. He worked as a Consultant gastroenterology and hepatology, King Fahd Hospital Madinah Monawarah. Currently, he is working as an Assistant professor of Internal Medicine Department, Faculty of Medicine, Mansoura University, Egypt\r\n\r\n

Background: Metabolic syndrome is increasing worldwide, and is increasing in women than men, and is increasing in parallel with increasing age and obesity. Dysglycemia is one of IDF 2006 criteria for definition of metabolic syndrome. Aim of the work is to evaluate the role of dysglycemia in cases of cerebral hemorrhage in patients with metabolic syndrome. \r\nPatients and methods: 240 patients presented with hemorrhagic stroke were divided into two groups according to IDF criteria (2006), full investigations, including laboratory investigations, ECG, chest x-ray and brain CT. \r\nResults and Conclusion: Among 240 patients with cerebral hemorrhage 77 patients have metabolic syndrome (32%), 22 patients had obesity, hypertension and dyslipidemia, 31 patients had obesity, hypertension and diabetes and 24 patients had all metabolic syndrome components. As regard dysglycemia, the presence of metabolic syndrome increases relative risk of dysglycemia by 2.5 fold in Met.s patients than non Met.s patients also, dysglycemia increases relative risk of mortality of cerebral hemorrhage with Met.s by 1.04 fold than with normal glucose tolerance.\r\n